
Признаки полярного Т3 синдрома у молодых мужчин в Якутии
Статья в журнале
Русский
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тиреотропный гормон (ТТГ); свободный трийодтиронин (св.Т3); свободный тироксин (св.Т4); Якутия; полярный Т3 синдром; thyroid-stimulating hormone (TSH) ; free triiodothyronine (fT3); free thyroxine (fT4); Yakutia; polar T3 syndrome
Медицина и здравоохранение / Клиническая медицина / Эндокринология медицинская. Расстройства питания и нарушения обмена веществ
Якутский медицинский журнал. – 2024. – 1 (85) (C. 5-8)
Seasonal variations in the levels of thyroid-stimulating hormone (TSH), free triiodothyronine (fT3) and free thyroxine (fT4) in young men in Yakutia were studied, where strong changes in climatic parameters in the winter-spring period (from -41.8°C to -0.2°C) were noted. Seasonal variations between winter and spring were found for fT3, where in winter its levels were lower - 6.48±0.31 pmol/L than in spring - 6.88±0.1 pmol/L (p=0.005). There were no statistically significant seasonal variations for TSH (U=97; p=0.914) and sv.T4 (U=47; p=0.112). Winter-spring seasonal variations of fT3 detected in this study there are signs of polar T3 syndrome in young men in Yakutia. To search for the causes of the detected seasonal variation, a correlation analysis of the levels of TSH, fT3 and fT4 was carried out depending on daylength and atmospheric air temperature. As a result, a correlation between fT3 and fT4 with the daylight (fT3: R=0.339, p=0.03; fT4: R=-0.346, p=0.01) and with air temperature (fT3: R=0.295, p=0.05; fT4: R=-0.296, p=0.04). No correlations were found with TSH levels (daylight: R=-0.06, p=0.69; air temperature: R=-0.09, p=0.559). Thus, the residents of Yakutia have signs of polar T3 syndrome, which can be associated with both a short light day and low atmospheric temperatures in winter. The results obtained may indicate an increase in the absorption of T3 at the tissue level when exposed to cold.
Признаки полярного Т3 синдрома у молодых мужчин в Якутии / А. А. Никанорова, Н. А. Барашков, В. Г. Пшенникова [и др.] ; Якутский научный центр комплексных медицинских проблем, Северо-Восточный федеральный университет им. М. К. Аммосова, Институт естественных наук // Якутский медицинский журнал. - 2024. - N 1 (85). - C. 5-8. - DOI: 10.25789/YMJ.2024.85.01
DOI: 10.25789/YMJ.2024.85.01
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